Overview Employment Education Digital Portfolio Publications
Employment Education Digital Portfolio Publications

Curriculum Vitae

Sarah J. Overby, Ph.D. Originally from Nashville, TN , Sarah  has been studying and working in Europe for the  past seven years specializing in bioinformatics   and experimental molecular genetics . Sarah is passionate about the impact of large-scale omics data on improvements to personalized medicine .

Overview

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Forensic Technician

2016

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Began Ph.D.

2018

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Awarded Doctoral degree

2022

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2015

Awarded Bachelor's degree
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2017

Awarded Master's Degree
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2020

International Mention
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Present

Post-Doctoral Researcher

  • Employment & Experience

    September 2022 - Present

    Research Scientist,

    Universitätsklinikum Frankfurt Frankfurt, Germany
    AG Brieger Laboratory Pioneering bioinformaticist leading the investigation of molecular mechanisms in colorectal cancer using large multi-omics patient data. Successfully engineered and deployed an R Shiny app for the exploration of large cancer databases.

    March - August 2022

    International Research Exchange,

    University of Oxford Oxford, U.K.
    Matthew Wood Group Mobilized and cultivated a partnership between two labs working towards the same goal of developing next-generation antisense drugs for the treatment of Myotonic Dystrophy Type 1 (DM1).

    September 2015 - August 2016

    Forensic Technician,

    Tennessee Bureau of Investigation Nashville, TN, USA
    Toxicology Laboratory Conducted drug detection immunoassays of blood evidence from criminal investigations using the ELISA technique.

Employment & Experience

September 2022 - Present

Research Scientist,

Universitätsklinikum Frankfurt
Frankfurt, Germany
AG Brieger Laboratory Pioneering bioinformaticist leading the investigation of molecular mechanisms in colorectal cancer using large multi-omics patient data. Successfully engineered and deployed an R Shiny app for the exploration of large cancer databases.

March - August 2022

International Research Exchange,

University of Oxford
Oxford, U.K.
Matthew Wood Group Mobilized and cultivated a partnership between two labs working towards the same goal of developing next-generation antisense drugs for the treatment of Myotonic Dystrophy Type 1 (DM1).

September 2015 - August 2016

Forensic Technician,

Tennessee Bureau of Investigation
Nashville, TN, USA
Toxicology Laboratory Conducted drug detection immunoassays of blood evidence from criminal investigations using the ELISA technique.

Education

Birmingham, AL, USA

B.A. Samford University

Spanish Major, Biology Minor Cum Laude
Dublin, Ireland
M.Sc. University College Dublin Specialization in Genetics and Cell Biology Upper Second Class Honours
Valencia, Spain
Ph.D. Universitat de València Biotechnology and Biomedicine Cum Laude - Sobresaliente ("Outstanding") International Mention

Education

Valencia, Spain
Ph.D. Universitat de València Biotechnology and Biomedicine Cum Laude - Sobresaliente ("Outstanding") International Mention
Dublin, Ireland
M.Sc. University College Dublin Specialization in Genetics and Cell Biology Upper Second Class Honours
Birmingham, AL, USA

B.A. Samford University

Spanish Major, Biology Minor Cum Laude

Digital Portfolio

Nanostring Microarray Analysis

In this R Markdown document, a Nanostring miRNA microarray experiment has been pre-processed and displayed for more detailed browsing. Differential expression data for each sample can be viewed with various interactive plots such as Heatmaply, ggVenn, and ggPlotly, as well as a small R Shiny app for searching for specific miRNA probes.

Geo-Omnibus Browser

Below is an R shiny app for accessing sequencing and array data from the NCBI GEO Omnibus database. By inputing experiment series, the user can choose specific samples from the series, browse for a target of interest, and apply the desired data transformation. Finally, the app generates an interactive plot as well as a data table with the values for the user to download.

Digital Portfolio

Nanostring Microarray Analysis

In this R Markdown document, a Nanostring miRNA microarray experiment has been pre-processed and displayed for more detailed browsing. Differential expression data for each sample can be viewed with various interactive plots such as Heatmaply, ggVenn, and ggPlotly, as well as a small R Shiny app for searching for specific miRNA probes.

Geo-Omnibus Browser

Below is an R shiny app for accessing sequencing and array data from the NCBI GEO Omnibus database. By inputing experiment series, the user can choose specific samples from the series, browse for a target of interest, and apply the desired data transformation. Finally, the app generates an interactive plot as well as a data table with the values for the user to download.